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鬼臼毒素
分析標(biāo)準(zhǔn)品,HPLC≥98%
Podophyllotoxin
CAS號(hào)：518-28-5
分子式：C22H22O8
分子量：414.41
MDL：MFCD00075290
貨號(hào) | 規(guī)格/參數(shù)/品牌 | 價(jià)格 | 貨期 |
YJ-B20477-20mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥200.00 | 現(xiàn)貨 |
YJ-B20477-100mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥550.00 | 現(xiàn)貨 |
YJ-B20477-500mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥1700.00 | 現(xiàn)貨 |
JS24887-1g | 98% | ￥168.00 | 現(xiàn)貨 |
JS24887-5g | 98% | ￥440.00 | 現(xiàn)貨 |
JS24887-25g | 98% | ￥1260.00 | 現(xiàn)貨 |
JS31341-20mg | 85%(HPLC) | ￥150.00 | 現(xiàn)貨 |
A10161-20mg | 分析標(biāo)準(zhǔn)品,含量94.3%，可溯源 | ￥280.00 | 現(xiàn)貨 |
產(chǎn)品介紹
Podofilox (Podophyllotoxin) 是微管組裝和DNA拓?fù)洚悩?gòu)酶II抑制劑。
熔點(diǎn)：183-184℃(lit.)
沸點(diǎn)：597.9℃ at 760 mmHg
比旋光度：-110.7 o (C=1, CHCL3)
外觀：白色針狀結(jié)晶粉末
溶解性：DMSO : 100 mg/mL (241.31 mM; Need ultrasonic)
儲(chǔ)存條件：2-8℃
注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。
參考文獻(xiàn)(16篇)
16. [IF=4.5] Lei Chen et al."Self-assembled ROS -responsive podollyllotoxin twin drug nanoparticles for enhanced anticancer therapy."JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY.2025 Mar;105:106650
15. [IF=13.3] Chaozheng Zhang et al."Dual targeting of FR+CD44 overexpressing tumors by self-assembled nanoparticles quantitatively conjugating folic acid-hyaluronic acid to the GSH-sensitively modified podophyllotoxin."CHEMICAL ENGINEERING JOURNAL.2025 Feb;505:159276
14. [IF=3.7] Min Wang et al."Characterizing the impact of podophyllotoxin on pulmonary toxicity and gut-lung microbiota interactions in SD rats based on TEC concept."Microbiology Spectrum.
13. [IF=4.4] Ma Kaiyue et al."Potential mechanisms underlying podophyllotoxin-induced cardiotoxicity in male rats: toxicological evidence chain (TEC) concept."Frontiers in Pharmacology.2024 Sep;15:
12. [IF=5.6] Shengnan Xu et al."Effects of age and tissue of Juniperus sabina L. on its phytochemical characteristics, anti-cholinesterase, antidiabetes, and anti-drug resistant bacteria activities."Frontiers in Plant Science.10.3389/fpls.2023.1174922
11. [IF=5.1] Hongyan Lin et al."Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC."JOURNAL OF NATURAL PRODUCTS.2023;XXXX(XXX):XXX-XXX
10. [IF=4.103] Yingyu Ma et al."Redox-responsive self-assembled podophyllotoxin twin drug nanoparticles for enhanced intracellular drug delivery."Biomedical Materials.2023 May;18(4):045019
9. [IF=4.384] Xiu Zhao et al."Preparation, characterization and biological evaluation of β-cyclodextrin-biotin conjugate based podophyllotoxin complex."Eur J Pharm Sci. 2021 May;160:105745
8. [IF=5.221] Zi Cheng-Ting et al."Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents."Front Chem. 2019 Jun;0:434
7. [IF=3.641] Cheng-Ting Zi et al."Synthesis and antitumor activity of novel per-butyrylated glycosides of podophyllotoxin and its derivatives."Bioorgan Med Chem. 2015 Apr;23:1437
6. [IF=5.64] Wu Dousheng et al."Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum."Front Microbiol. 2015 Dec;0:1466
5. Zi, Cheng-Ting, et al. "Synthesis and Anticancer Activity of 4 β-Triazole-podophyllotoxin Glycosides." Natural products and bioprospecting 5.2 (2015): 83-90.
4. 范素芳, 馬俊美, 劉茁,等. 高效液相色譜-串聯(lián)質(zhì)譜測定食品中15種有毒生物堿[J]. 食品科學(xué), 2018, 39(22):290-295.
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2. 山金鳳, 劉寧芝, 杜欣韻,等. 鬼臼甘草配伍有效成分提取工藝的研究[J]. 現(xiàn)代化工, 2016(12):47-50.
1. 王萍 陳濤 劉永玲 等. 響應(yīng)面法優(yōu)化桃兒七中鬼臼毒素的熱回流提取工藝[J]. 中藥材 2012 35(011):1864-1867.
